Which of the following signs is associated with asthma in children?

• A. Abdominal tenderness
• B. Elevated ALT/AST
• C. Fatigue
• D. SOB and exercise intolerance

Answer: (D)

Asthma in children presents with reversible airway obstruction that shows up as trouble breathing, especially during activity or with triggers. Shortness of breath with exercise intolerance directly reflects the way the airways narrow during an asthma flare, making it hard to keep up with activity and causing breathing difficulty.

The other signs don’t fit as well. Abdominal tenderness points toward GI issues rather than airway problems. Elevated liver enzymes indicate liver stress or injury, not asthma. Fatigue can occur in many conditions and isn’t a hallmark feature of asthma on its own. So, shortness of breath and exercise intolerance best capture the classic respiratory limitation seen in pediatric asthma.