Which signal from ileum and colon is anorexigenic?

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Multiple Choice

Which signal from ileum and colon is anorexigenic?

Explanation:
The main idea is how gut hormones tell the brain to regulate appetite after eating. From the distal gut, a key signal that makes you feel full is peptide YY, released by L-cells in the ileum and colon after a meal. PYY travels to the brain and activates receptors that dampen hunger signals, helping reduce food intake. It also contributes to slowing gut movement, which reinforces the feeling of fullness. Leptin comes from fat tissue and reflects longer-term energy stores, not immediate meal response. Ghrelin, mainly from the stomach, increases hunger rather than suppressing it. GLP-1 is another distal-gut hormone that can reduce appetite, but the question highlights the classic anorexigenic signal specific to the ileum and colon, which is PYY.

The main idea is how gut hormones tell the brain to regulate appetite after eating. From the distal gut, a key signal that makes you feel full is peptide YY, released by L-cells in the ileum and colon after a meal. PYY travels to the brain and activates receptors that dampen hunger signals, helping reduce food intake. It also contributes to slowing gut movement, which reinforces the feeling of fullness.

Leptin comes from fat tissue and reflects longer-term energy stores, not immediate meal response. Ghrelin, mainly from the stomach, increases hunger rather than suppressing it. GLP-1 is another distal-gut hormone that can reduce appetite, but the question highlights the classic anorexigenic signal specific to the ileum and colon, which is PYY.

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